A novel high throughput invasion screen identifies host actin regulators required for efficient cell entry by Toxoplasma gondii.
Toxoplasma gondii critically relies on cell invasion as a survival strategy to evade immune clearance during infection.Although it was widely thought that Toxoplasma entry is parasite directed and that the host cell is largely a passive victim, recent studies have suggested that host components such as microfilaments and read more microtubules inde